Plant Extract White Powder Cyclopamine is a Steroidal Alkaloid

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Plant Extract White Powder Cyclopamine is a Steroidal Alkaloid

Source and extraction method：

Source: Cyclopamine is mainly derived from plants such as Veratrum californicum. Veratrum is a plant of the genus Veratrum in the Liliaceae family. The plant can reach 1 meter in height, with short and thick rhizomes and many fleshy fibrous roots. The stem is upright, cylindrical, and has longitudinal stripes. The leaves are alternate, and the leaves are elliptical or ovate-lanceolate. The inflorescence is panicle, and the perianth segments are black and purple. The roots and rhizomes of Veratrum are the main parts for extracting cyclopamine.

Extraction method:

Organic solvent extraction method: Commonly used organic solvents include ethanol, methanol, chloroform, etc. Generally, the roots and rhizomes of Veratrum are dried and crushed, and then soaked and refluxed with organic solvents for extraction. For example, ethanol solution is soaked and heated to reflux to dissolve cyclopamine in the solvent. After filtration, concentration and other operations, an extract containing cyclopamine is obtained. Then it is further purified by column chromatography, recrystallization and other methods to obtain cyclopamine with higher purity.

Supercritical fluid extraction: Using carbon dioxide in a supercritical state as an extractant, supercritical carbon dioxide has good solvent properties and high diffusivity. By adjusting the temperature, pressure and adding an appropriate amount of entrainer (such as ethanol), cyclopamine can be selectively extracted, and organic solvent residues can be avoided to improve the quality of the extract, but the equipment cost is relatively high.

Plant Extract White Powder Cyclopamine is a Steroidal Alkaloid

Product Information

Cyclopamine is a steroidal alkaloid with a complex chemical structure. It belongs to the cyclopentane polyhydrophenanthrene derivative. It contains a steroidal nucleus with multiple functional groups attached to it and has a unique cyclopropane structure with a molecular formula of . This structure gives cyclopamine a variety of special chemical and biological activities.

Physical properties: It is usually a white crystalline solid and odorless. In terms of solubility, cyclopamine has poor solubility in water and has certain solubility in organic solvents such as methanol, ethanol, chloroform, etc. The melting point is around 248-250℃, and the chemical properties are relatively stable, but chemical reactions may occur under strong acidic or alkaline conditions.

Chemical properties: Due to the functional groups in its structure, cyclopamine can undergo a variety of chemical reactions. For example, the amino groups it contains can react with acids to form salts. This property can be used to chemically modify it in medicinal chemistry research to improve its solubility and bioavailability.

Plant Extract White Powder Cyclopamine is a Steroidal Alkaloid

Shaanxi Baisfu Bioengineering Co., Ltd. is an enterprise specializing in the research and development, production and sales of flavors and fragrances. The company is located in Building A, Baodeyun Valley, No. 52, Jinye 1st Road, Yanta District, Xi'an City, Shaanxi Province. It has an excellent geographical location and convenient transportation. convenient. The company was established in December 2019, with a registered capital of 3 million yuan.

Shaanxi Baisfu Bioengineering Co., Ltd，The company's main products include cooling agents, synthetic flavors and natural flavors. The company's products can be used in food and beverage, 

daily chemical, and other industries, and have a wide range of downstream applications.

The company always attaches great importance to product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001, kosher, and HALAL European analysis.

The company's products are used by more than 30 foreign companies and regions. After more than ten years of technology accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and has established relationships with more than 100 domestic and foreign companies. Good working relations.

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